4000-520-616
欢迎来到免疫在线!(蚂蚁淘生物旗下平台)  请登录 |  免费注册 |  询价篮
主营:主营:防癌抗癌特殊化学品试剂
咨询热线电话
4000-520-616
当前位置: 首页 > 产品中心 > clinical_research > LKT/(+)-CATECHIN/C0278/5 mg
商品详细LKT/(+)-CATECHIN/C0278/5 mg
LKT/(+)-CATECHIN/C0278/5 mg
LKT/(+)-CATECHIN/C0278/5 mg
商品编号: C0278-5mg
品牌: lktlabs
市场价: ¥3160.00
美元价: 1896.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

CatechinisaflavanoloriginallyfoundinCamillaandotherplantsources;itexhibitsantioxidative,anti-aging,anti-atherosclerotic,anti-ulcerative,neuroprotective,neuromodulatory,anticancerchemotherapeutic,andchemopreventiveactivities.CatechinincreaseslifespaninCaenorhaBDitiselegansandinhibitsmonoamineoxidaseB(MAO-B)invitro.Catechindecreasesatheroscleroticlesionarea,suppressesleukocyteadhesion,andinhibitsLDLoxidationanduptakeinanimalmodelsofatherosclerosis.Inanimalmodelsofbrainhemorrhage,catechinincreasersactivityofNrf2andphaseIIdetoxifyingenzymes,inhibitingoxidativestress,neurologicaldeficits,andlesionformation.Inotheranimalmodels,catechininhibitshistidinedecarboxylase,decreasinggastriclesionformation.Additionally,catechinincreasesmusclefatigueresistanceandexercisecapacityinvivo.ThiscompoundalsodecreasestumornumberandformationandsuppressesphosphorylationofFAKinanimalmodelsofcolorectalcancer.

ProductInfo

CasNo.

154-23-4

Purity

≥99%

Formula

C15H14O6

FormulaWt.

290.27

ChemicalName

(2R-trans)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol

IUPACName

(2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol

Synonym

Catechol;Catechinicacid;Dexcyanidanol;Cyanidol;Catergen

MeltingPoint

93-96°C

Solubility

Solubleinhotwater,alcoholacetone,andglacialaceticacid.

Appearance

Faintlybrownpowder

ShippingandStorage

StoreTemp

-20°C

ShipTemp

Ambient

Downloads

MSDS

C0278MSDSPDF

InfoSheet

C0278InfoSheetPDF

Brochures

GreenTeaFlyer

Brochures

NaturalProductsFlyer

References

ChangCF,ChoS,WangJ.(-)-EpicatechinprotectshemorrhagicbrainviasynergisticNrf2pathways.AnnClinTranslNeurol.2014Apr1;1(4):258-271.PMID:24741667.

NogueiraL,Ramirez-SanchezI,PerkinsGA,etal.(-)-Epicatechinenhancesfatigueresistanceandoxidativecapacityinmousemuscle.JPhysiol.2011Sep15;589(Pt18):4615-31.PMID:21788351.

SaulN,PietschK,MenzelR,etal.CatechininducedlongevityinC.elegans:fromkeyregulatorgenestodisposablesoma.MechAgeingDev.2009Aug;130(8):477-86.PMID:19501612.

AuclairS,MilenkovicD,BessonC,etal.CatechinreducesatheroscleroticlesiondevelopmentinapoE-deficientmice:atranscriptomicstudy.Atherosclerosis.2009Jun;204(2):e21-7.PMID:19152914.

HouWC,LinRD,ChenCT,etal.MonoamineoxidaseB(MAO-B)inhibitionbyactiveprinciplesfromUncariarhynchophylla.JEthnopharmacol.2005Aug22;100(1-2):216-20.PMID:15890481.

WeyantMJ,CarothersAM,DannenbergAJ,etal.(+)-Catechininhibitsintestinaltumorformationandsuppressesfocaladhesionkinaseactivationinthemin/+mouse.CancerRes.2001Jan1;61(1):118-25.PMID:11196148.

MangiapaneH,ThomsonJ,SalterA,etal.Theinhibitionoftheoxidationoflowdensitylipoproteinby(+)-catechin,anaturallyoccurringflavonoid.BiochemPharmacol.1992Feb4;43(3):445-50.PMID:1540202.

ReimannHJ,LorenzW,FischerM,etal.Histamineandacutehaemorrhagiclesionsinratgastricmucosa:preventionofstressulcerformationby(+)-catechin,aninhibitorofspecifichistidinedecarboxylaseinvitro.AgentsActions.1977Mar;7(1):69-73.PMID:871094.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂