LKT/（+）-紫杉醇/T0394/100毫克-免疫在线蚂蚁淘旗下平台

商品详细LKT/（+）-紫杉醇/T0394/100毫克

LKT/（+）-紫杉醇/T0394/100毫克

商品编号： T0394-100mg

品牌： lktlabs

市场价： ¥4100.00

美元价： 2460.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDT0394

CasNo.480-18-2

Purity≥92%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Taxifolinisacatechol-typeflavonoidthatdisplayscardioprotective,neuroprotective,antioxidative,andanticancerchemotherapeuticactivities.Inanimalmodelsofdiabeticcardiomyopathy,taxifolininhibitsmyocyteapoptosis(throughinhibitionofcaspase-3andcaspase-9activation,releaseofcytochromec,andincreasesinJAK/STAT3activation),attenuatingstructuralpathologyandimprovingdiastolicfunction.TaxifolindisplaysneuroprotectivepropertiesinmodelsofAlzheimer’sdiseaseasitpreventsaggregationofamyloid-β(Aβ)proteinsbyreactingwithlysineresidues.ThiscompoundalsoincreasesquinonereductaseactivityanddecreasesNADPHoxidaseactivity,activatingtheantioxidantresponseelement(ARE).Additionally,taxifolininhibitsfattyacidsynthesisandcellgrowthandinducesapoptosis,inhibitingproliferationofcancercellsinvitroandinvivo.

ProductInfo

CasNo.	480-18-2
Purity	≥92%
Formula	C₁₅H₁₂O₇
FormulaWt.	304.25
IUPACName	(2S,3S)-2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-2,3-dihydro-4H-chromen-4-one
Appearance	Lightyellowpowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

InfoSheet	T0394InfoSheetPDF

References

SunX,ChenRC,YangZH,etal.Taxifolinpreventsdiabeticcardiomyopathyinvivoandinvitrobyinhibitionofoxidativestressandcellapoptosis.FoodChemToxicol.2013Nov20.[Epubaheadofprint].PMID:24269735

SatoM,MurakamiK,UnoM,etal.Site-specificinhibitorymechanismforamyloidβ42aggregationbycatechol-typeflavonoidstargetingtheLysresidues.JBiolChem.2013Aug9;288(32):23212-24.PMID:23792961

LeeSB,ChaKH,SelengeD,etal.ThechemopreventiveeffectoftaxifolinisexertedthroughARE-dependentgeneregulation.BiolPharmBull.2007Jun;30(6):1074-9.PMID:17541156

BrusselmansK,VrolixR,VerhoevenG,etal.InductionofcancercellapoptosisbyflavonoidsisassociatedwiththeirABIlitytoinhibitfattyacidsynthaseactivity.JBiolChem.2005Feb18;280(7):5636-45.PMID:15533929.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂