(-)-Epicatechin(EC)isaflavanolandcatechinoriginallyfoundinCamillaandotherplantsources;itexhibitsantioxidative,neuroprotective,anti-atherosclerotic,andcardioprotectiveactivities.Inanimalmodelsofmyocardialischemia/reperfusion,ECdecreaseinfarctsizeandimprovesmitochondrialrespiration.InanimalmodelsofAlzheimer’sdisease,ECdecreaseslevelsofamyloid-β(Aβ)inthebrainandserum,suppressingneuroinflammation.ECalsodecreasesatheroscleroticlesionarea,loweringlevelsofSAAandCRPinvivo.
| CasNo. | 490-46-0 |
|---|---|
| Purity | ≥93% |
| Formula | C15H14O6 |
| FormulaWt. | 290.27 |
| ChemicalName | 2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzo-pyran-3,5,7-triol |
| IUPACName | (2R,3R)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol |
| Synonym | Epicatechin;Epicatechol |
| MeltingPoint | 240°C(dec) |
| Solubility | Solubleinwateroralcohol. |
| Appearance | WhiteCrystalPowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| MSDS | E6231MSDSPDF |
|---|---|
| InfoSheet | E6231InfoSheetPDF |
| Brochures | GreenTeaFlyer |
| Brochures | NaturalProductsFlyer |
YamazakiKG,AndreyevAY,Ortiz-VilchisP,etal.Intravenous(-)-epicatechinreducesmyocardialischemicinjurybyprotectingmitochondrialfunction.IntJCardiol.2014Aug1;175(2):297-306.PMID:24908200.
ZengYQ,WangYJ,ZhouXF.Effectsof(-)EpicatechinonthePathologyofAPP/PS1TransgenicMice.FrontNeurol.2014May9;5:69.PMID:24847308.
MorrisonM,vanderHeijdenR,HeeringaP,etal.Epicatechinattenuatesatherosclerosisandexertsanti-inflammatoryeffectsondiet-inducedhuman-CRPandNFκBinvivo.Atherosclerosis.2014Mar;233(1):149-56.PMID:24529136.
ButtMS,AhmadRS,SultanMT,etal.Greenteaandanticancerperspectives:Updatesfromlastdecade.CritRevFoodSciNutr.2013Sep20.[Epubaheadofprint].PMID:24915354.
