LKT/3,4-DIHYDROXYPHENYL ETHANOL/D3431/100 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/3,4-DIHYDROXYPHENYL ETHANOL/D3431/100 mg

LKT/3,4-DIHYDROXYPHENYL ETHANOL/D3431/100 mg

商品编号： D3431-100mg

品牌： lktlabs

市场价： ¥11360.00

美元价： 6816.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDD3431

CasNo.10597-60-1

Purity≥95%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

3,4-Dihydroxyphenolethanol,alsoknownas3-hydroxytyrosol,isapolyphenoloriginallyfoundinoliveoil.3-Hydroxytyrosolexhibitsantioxidative,anti-inflammatory,anti-hyperlipidemic,anti-diabetic,anti-platelet,andanticancerchemotherapeuticactivities.Inbrainslicesundergoinghypoxiaandreoxygenation,3-hydroxytyrosolincreasesrADIcalscavengingandglutathioneactivityanddecreaseslipidperoxidationandexpressionofprostaglandinE2(PGE2)andIL-1β.3-HydroxytyrosolalsodecreasesexpressionofprostaglandinE2(PGE2),matrixmetalloproteinase9(MMP9),andCOX-2throughinhibitionofPKCactivationandNF-κBtranslocation.Inanimalmodelsofdiabetes,3-hydroxytyrosolinhibitsSREBP/Fassignalingtodecreaselipiddepositsandinhibitsmitochondrialapoptosis,resultingindecreasesinfastingglucose,serumlipidlevels,andlipidoxidation.Inwholebloodandplasma,thiscompoundinhibitsplateletaggregation,inhibitingproductionofthromboxaneB2,TNF-α,andleukocyte6-keto-PGF1.Additionally,3-hydroxytyrosolinhibitsproliferationofcholangiocarcinomacellsinvitroandinhibitstumorgrowthofxenograftsinvivo.

ProductInfo

CasNo.	10597-60-1
Purity	≥95%
Formula	C₈H₁₀O₃
FormulaWt.	154.16
ChemicalName	2-(3,4-Dihydroxyphenyl)ethylalcohol
IUPACName	4-(2-hydroxyethyl)benzene-1,2-diol
Synonym	3-Hydroxytyrosol
Solubility	Freelysolubleinorganicsolvents.Slightlysolubleinwater(5g/100ml)at25oC.
Appearance	Lightyellowviscousliquid

ShippingandStorage

StoreTemp	4°C
ShipTemp	Ambient

Downloads

InfoSheet	D3431InfoSheetPDF

References

ScodittiE,NestolaA,MassaroM,etal.HydroxytyrosolsuppressesMMP-9andCOX-2activityandexpressioninactivatedhumanmonocytesviaPKCαandPKCβ1inhibition.Atherosclerosis.2014Jan;232(1):17-24.PMID:24401212.

CaoK,XuJ,ZouX,etal.Hydroxytyrosolpreventsdiet-inducedmetabolicsyndromeandattenuatesmitochondrialabnormalitiesinobesemice.FreeRadicBiolMed.2013Dec6;67C:396-407.PMID:24316371.

LiS,HanZ,MaY,etal.Hydroxytyrosolinhibitscholangiocarcinomatumorgrowth:Aninvivoandinvitrostudy.OncolRep.2014Jan;31(1):145-52.PMID:24247752.

CabrerizoS,DeLaCruzJP,López-VillodresJA,etal.Roleoftheinhibitionofoxidativestressandinflammatorymediatorsintheneuroprotectiveeffectsofhydroxytyrosolinratbrainslicessubjectedtohypoxiareoxygenation.JNutrBiochem.2013Dec;24(12):2152-7.PMID:24231104.

CorreaJA,López-VillodresJA,AsensiR,etal.Virginoliveoilpolyphenolhydroxytyrosolacetateinhibitsinvitroplateletaggregationinhumanwholeblood:comparisonwithhydroxytyrosolandacetylsalicylicacid.BrJNutr.2009Apr;101(8):1157-64.PMID:18775097.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂