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当前位置: 首页 > 产品中心 > clinical_research > LKT/[GLN8]-LUTEINIZING HORMONE RELEASING HORMONE, CHICKEN/L8277/5 mg
商品详细LKT/[GLN8]-LUTEINIZING HORMONE RELEASING HORMONE, CHICKEN/L8277/5 mg
LKT/[GLN8]-LUTEINIZING HORMONE RELEASING HORMONE, CHICKEN/L8277/5 mg
LKT/[GLN8]-LUTEINIZING HORMONE RELEASING HORMONE, CHICKEN/L8277/5 mg
商品编号: L8277-5mg
品牌: lktlabs
市场价: ¥3780.00
美元价: 2268.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Luteinizinghormone-releasinghormone(LHRHorGonadotropin-releasinghormone[GnRH])isanendogenouspeptidehormonethatbindstheGnRHreceptor,stimulatingsecretionofreproductivehormones(suchasluteinizinghormone[LH]andfollicle-stimulatinghormone[FSH])fromthepituitarygland.AnalogsofGnRHareclinicallyusedtotreathormone-dependentdiseasessuchasprostateandbreastcancer,hyperplasia,andendometriosis.

ProductInfo

CasNo.

47922-48-5

Purity

≥95%

Formula

C54H71N15O14

FormulaWt.

1154.28

IUPACName

(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-5-amino-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

Synonym

LHRH;GnRH

Appearance

Whitetooffwhitepowder

ShippingandStorage

StoreTemp

-20°C

ShipTemp

Ambient

Downloads

MSDS

L8277MSDSPDF

InfoSheet

L8277InfoSheetPDF

References

LimontaP,ManeaM.Gonadotropin-releasinghormonereceptorsasmoleculartherapeutictargetsinprostatecancer:Currentoptionsandemergingstrategies.CancerTreatRev.2013Oct;39(6):647-63.PMID:23290320.

MillarRP,NewtonCL.CurrentandfutureapplicationsofGnRH,kisspeptinandneurokininBanalogues.NatRevEndocrinol.2013Aug;9(8):451-66.PMID:23817290.

WuHM,WangHS,HuangHY,etal.Gonadotropin-releasinghormonetypeII(GnRH-II)agoNISTregulatestheinvasivenessofendometrialcancercellsthroughtheGnRH-Ireceptorandmitogen-activatedproteinkinase(MAPK)-dependentactivationofmatrixmetalloproteinase(MMP)-2.BMCCancer.2013Jun20;13:300.PMID:23786715.

BurelD,LiJH,Do-RegoJL,etal.Gonadotropin-releasinghormonestimulatesthebiosynthesisofpregnenolonesulfateanddehydroepiandrosteronesulfateinthehypothalamus.Endocrinology.2013Jun;154(6):2114-28.PMID:23554453.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂