Angiotensin III (AT III) is the smallest, least active peptide fragment of precursor angiotensinogen. AT III is produced by the degradation of AT II by angiotensinase. AT III has 40% of the vasoconstrictive pressor activity of AT II but increases aldosterone secretion and mean arterial pressure through activity at the AT II type 1 (AT1) receptor.
| Cas No. | 52498-25-6 |
|---|---|
| Purity | ≥95% |
| Formula | C43H68N12O9 |
| Formula Wt. | 897.1 |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | A5285 Info Sheet PDF |
|---|
Yugandhar VG, Clark MA. Angiotensin III: a physiological relevant peptide of the renin angiotensin system. Peptides. 2013 Aug;46:26-32. PMID: 23692861.
Yang R, Smolders I, Dupont AG. Blood pressure and renal hemodynamic effects of angiotensin fragments. Hypertens Res. 2011 Jun;34(6):674-83. PMID: 21412242.
Dupont AG, Brouwers S. Brain angiotensin peptides regulate sympathetic tone and blood pressure. J Hypertens. 2010 Aug;28(8):1599-610. PMID: 20502352.
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