10-DeacetybaccatinIIIisaditerpenefoundinTaxusthatexhibitsanalgesic,anti-inflammatory,andanti-parasiticactivities.Invivo,thiscompounddecreasesedemaaswellaspainscoresintheacid-inducedwritingtest.10-DeacetylbaccatinIIIalsoinducesG2/MphasecellcyclearrestandinhibitsgrowthinLeishmania.
| CasNo. | 32981-86-5 |
|---|---|
| Purity | ≥98% |
| Formula | C29H36O10 |
| FormulaWt. | 544.59 |
| Synonym | 10-DBIII;10-DeacetylbaccatineIII;DocetaxelimpurityE. |
| MeltingPoint | 230-233°C |
| Solubility | SolubleinDMSO. |
| Appearance | Whitetooffwhitecrystallinepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| MSDS | T0099MSDSPDF |
|---|---|
| InfoSheet | T0099InfoSheetPDF |
QayumM,NisarM,ShahMR,etal.AnalgesicandantiinflammatoryactivitiesoftaxoidsfromTaxuswallichianaZucc.PhytotherRes.2012Apr;26(4):552-6.PMID:21953729.
GeorgopoulouK,SmirlisD,BistiS,etal.Invitroactivityof10-deacetylbaccatinIIIagainstLeishmaniadonovanipromastigotesandintracellularamastigotes.PlantaMed.2007Aug;73(10):1081-8.PMID:17691059.
