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当前位置: 首页 > 产品中心 > clinical_research > LKT/20R-GINSENOSIDE RH2/G3558/10 mg
商品详细LKT/20R-GINSENOSIDE RH2/G3558/10 mg
LKT/20R-GINSENOSIDE RH2/G3558/10 mg
LKT/20R-GINSENOSIDE RH2/G3558/10 mg
商品编号: G3558-10mg
品牌: lktlabs
市场价: ¥8120.00
美元价: 4872.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

GinsenosideRh4isatriterpenesaponinfoundinPanax(ginseng)thatexhibitsimmunomodulatory,neuroprotective,cognitionenhancing,anti-inflammatory,antioxidative,andanticanceractivities.InCD8+Tcells,ginsenosideRh4increasesproductionofIFN-γandactivationofp38MAPKandERK,resultinginanincreaseincellproliferation.InanimalsundergoingtheMorriswatermazetest,ginsenosideRh4improvesspatiallearningandmemory.ThiscompoundalsomodulatesexpressionofinflammatoryMarkers,decreasingexpressionoftoll-likereceptor4(TLR4),CD14,TNF-α,IL-1αandHIF-1α,andinhibitingdegradationofIκBkinaseandtranslocationofNF-κBacrossvariouscellularmodels.

ProductInfo

CasNo.

112246-15-8

Purity

≥98%

Formula

C36H62O8

FormulaWt.

622.87

IUPACName

(2R,3R,4S,5S,6R)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxane-3,4,5-triol

Synonym

GinsenosideRh4

Appearance

Whitetooffwhitepowder

ShippingandStorage

StoreTemp

4°C

ShipTemp

Ambient

Downloads

MSDS

G3558MSDSPDF

InfoSheet

G3558InfoSheetPDF

References

LvS,YiPF,ShenHQ,etal.GinsenosideRh4-B1stimulatescellproliferationandIFN-γproductionbyactivatingthep38MAPKandERK-dependentsignalingpathwaysinCTLL-2cells.ImmunopharmacolImmunotoxicol.2013Dec3.[Epubaheadofprint].PMID:24294901.

HouJ,XueJ,LeeM,etal.GinsenosideRh4improveslearningandmemoryinmice.JMedFood.2013Aug;16(8):772-6.PMID:23957360.

TangXP,TangGD,FangCY,etal.EffectsofginsenosideRh4ongrowthandmigrationofpancreaticcancercells.WorldJGastroenterol.2013Mar14;19(10):1582-92.PMID:23538603.

LianLH,JinQ,SongSZ,etal.GinsenosideRh4DownregulatesLPS-InducedNF-κBActivationthroughInhibitionofTAK1PhosphorylationinRAW264.7MurineMacrophage.EvidBasedComplementAlternatMed.2013;2013:646728.PMID:23483870.

ChoiWY,LimHW,LimCJ.Anti-inflammatory,antioxidativeandmatrixmetalloproteinaseinhibitorypropertiesof20(R)-ginsenosideRh4inculturedmacrophagesandkeratinocytes.JPharmPharmacol.2013Feb;65(2):310-6.PMID:23278699.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂