4-Aminosalicylicacidexhibitsanti-inflammatory,antioxidative,andantibacterialactivities;itisclinicallyusedtotreatinflammatoryboweldisease(IBD),Crohn’sdisease,andcolitis,asitactsprimarilyinthecolon.4-AminosalicylicacidisusedagainstMycobacteriumasatreatmentfortuberculosis;itinhibitsdihydrofolatereductase(DHFR)activityasanantimetabolite.
| CasNo. | 65-49-6 |
|---|---|
| Purity | ≥98% |
| Formula | C7H7NO3 |
| FormulaWt. | 153.14 |
| ChemicalName | 4-Amino-2-hydroxybenzoicacid |
| IUPACName | 4-amino-2-hydroxybenzoicacid |
| Synonym | p-AminosalicylicAcid;PASER;Rezipas |
| MeltingPoint | 150-151°C |
| Solubility | Solubleinwaterandalcohol.Practicallyinsolubleinbenzene. |
| Appearance | Awhiteoralmostwhitecrystallinepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | A5033MSDSPDF |
|---|---|
| InfoSheet | A5033InfoSheetPDF |
DhaneshwarSS.Colon-specificprodrugsof4-aminosalicylicacidforinflammatoryboweldisease.WorldJGastroenterol.2014Apr7;20(13):3564-71.PMID:24707139.
JensenKA,RosdahlKG,IngvorsenH.Tuberculostaticderivativesofrho-aminobenzoicacid;estersandamidesof4-aminosalicylicacid.ActaChemScand.1948;2(3):220-4.PMID:18098531.
