BicucullineisaneuromodulatoryGABA-AreceptorantagoNISTusedtostudyregionalvariationofGABAreceptorsandtheroleofGABA-Areceptorsinmotordisorders,pain,seizure,nociception,anxiety,andmemory.ThroughitsinhibitionofGABA-Areceptors,bicucullinepotentiatesactivationatNMDAreceptorsandproducesmembranedepolarization,inhibitingK+conductanceandprolongingCa2+-dependentactionpotentialsinneurons.Specificrotation+130(20D,chloroformc=2)
| CasNo. | 485-49-4 |
|---|---|
| Purity | ≥98% |
| Formula | C20H17NO6 |
| FormulaWt. | 367.35 |
| IUPACName | (6R)-6-[(5S)-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | B3211InfoSheetPDF |
|---|
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