3H-1,2-dithiole-3-thione(D3T)isaphaseIIenzymeinducerandsulfurdonororiginallyfoundincruciferousvegetables;itexhibitsantioxidative,neuroprotective,andchemopreventiveactivities.Invitro,D3TincreaseslevelsofglutathioneandactivityofNADHquinoneoxidoreductase(NQO1),protectingcellsagainstH2O2-inducedtoxicity.D3TalsoinducesactivationofNrf2,inhibitingethanol-inducedapoptosisinneurons.Additionally,thiscompoundinhibitstheformationofDNAadductsbyDBPinbreastcancercells.
| CasNo. | 534-25-8 |
|---|---|
| Purity | ≥98% |
| Formula | C3H2S3 |
| FormulaWt. | 134.25 |
| IUPACName | dithiole-3-thione |
| Synonym | D3T;1,2-Dithiol-3-thione |
| Solubility | Insolubleinwater.SolubleinDMSO(≥10mg/ml). |
| Appearance | Darkredcrystals |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | D0010MSDSPDF |
|---|---|
| InfoSheet | D0010InfoSheetPDF |
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