4-Bromoflavonedisplaysantioxidativeandchemopreventiveactivities.4-BromoflavoneactivatesNrf2-Keap1-AREcomplexsignalingandalsoinducesquinonereductaseandotherphaseIIenzymes.Additionally,thiscompoundpreventsthedevelopmentofmammarytumors,increasingtumorlatencyinvivo.
| CasNo. | 1218-80-0 |
|---|---|
| Purity | ≥98% |
| Formula | C15H9BrO2 |
| FormulaWt. | 301.13 |
| IUPACName | 6-bromo-2-phenylchromen-4-one |
| Synonym | 6-Bromo-2-phenylbenzopyran;6-Bromo-2-pheynyl-4H-1-benzopyran-4-one;6-Bromoflavone |
| MeltingPoint | 176-178°C(lit.) |
| Appearance | Off-Whitecrystallinepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | B6857MSDSPDF |
|---|---|
| InfoSheet | B6857InfoSheetPDF |
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SongLL,KosmederJW2nd,LeeSK,etal.Cancerchemopreventiveactivitymediatedby4"-bromoflavone,apotentinducerofphaseIIdetoxificationenzymes.CancerRes.1999Feb1;59(3):578-85.PMID:9973203.
