Description
4-Phenylbutylisothiocyanate(ITC)isasyntheticITCthatexhibitsanticancerchemotherapeuticandchemopreventiveactivities.Invitro,thiscompoundinducescaspase3-dependentapoptosis.4-Phenylbutylisothiocyanateinhibitsthedevelopmentofpancreaticdysplasiaandadenocarcinomainanimalmodels;inotheranimals,itdecreasesthenumberofalreadyformedlungtumors.LikeotherITCs,thiscompoundalsoactsasaphaseIIenzymeinducer.