Description
4’-Demethylepipodophyllotoxin is a topoisomerase II inhibitor found in Podophyllum. Derivatives of this compound exhibit anticancer chemotherapeutic activity.
LKT/4U2032-DEMETHYLEPIPODOPHYLLOTOXIN/D1849/500 mg
商品编号：
D1849-500mg
品牌：
lktlabs
市场价：
¥1940.00
美元价：
1164.00
产品分类：
临床研究
公司分类：
clinical_research
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Product ID D1849
Cas No. 6559-91-7
Purity ≥98%
- Description
- Product Info
- Shipping and Storage
- Downloads
- References
Product Info
| Cas No. | 6559-91-7 |
|---|---|
| Purity | ≥98% |
| Formula | C21H20O8 |
| Formula Wt. | 400.38 |
| Chemical Name | Furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5ah)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R-(5-alpha,5a-beta,8a-alpha,9-beta))- |
| IUPAC Name | (5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one |
| Melting Point | 246-248°C |
| Appearance | White Cystal Powder |
Shipping and Storage
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | D1849 MSDS PDF |
|---|---|
| Info Sheet | D1849 Info Sheet PDF |
References
Xiao L, Zhao W, Li HM, et al. Design and synthesis of the novel DNA topoisomerase II inhibitors: esterification and amination substituted 4'-demethylepipodophyllotoxin derivates exhibiting anti-tumor activity by activating ATM/ATR signaling pathways. Eur J Med Chem. 2014 Jun 10;80:267-77. PMID: 24793877.
Yang TM, Guo SF, Chen CR, et al. Anti-osteosarcoma effects and mechanisms of 4-O-amino-phenol-4'-demethylepipodophyllotoxin ether. J Pharm Pharmacol. 2008 Feb;60(2):179-88. PMID: 18237465.
品牌介绍
LKT Labs
LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。
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