Description
Thiscompoundisaderivativeofcephalomannine,foundinspeciesofTaxus.Likeothertaxanes,thiscompoundmayinhibitDNApolymeraseandmicrotubuledepolymerization,exhibitinganticanceractivity.
Thiscompoundisaderivativeofcephalomannine,foundinspeciesofTaxus.Likeothertaxanes,thiscompoundmayinhibitDNApolymeraseandmicrotubuledepolymerization,exhibitinganticanceractivity.
Purity | ≥95% |
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Formula | C45H53NO14 |
FormulaWt. | 831.9 |
Appearance | Whitetooffwhitepowder |
StoreTemp | -20°C |
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ShipTemp | Ambient |
MSDS | T0118MSDSPDF |
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InfoSheet | T0118InfoSheetPDF |
LiY,QinF,WangSM,etal.ChemicalstudiesonTaxuscanadensis.ChemBiodivers.2013Oct;10(10):1729-53.PMID:24130020.
OshigeM,TakenouchiM,KatoY,etal.TaxolderivativesareselectiveinhibitorsofDNApolymerasealpha.BioorgMedChem.2004May15;12(10):2597-601.PMID:15110841.
PandeyRC,YankovLK,PoulevA,etal.SynthesisandseparationofpotentialanticanceractivedihalocephalomanninediastereomersfromextractsofTaxusyunnanensis.JNatProd.1998Jan;61(1):57-63.PMID:9461653.