Description
Thiscompoundisaderivativeofcephalomannine,foundinspeciesofTaxus.Likeothertaxanes,thiscompoundmayinhibitDNApolymeraseandmicrotubuledepolymerization,exhibitinganticanceractivity.
Thiscompoundisaderivativeofcephalomannine,foundinspeciesofTaxus.Likeothertaxanes,thiscompoundmayinhibitDNApolymeraseandmicrotubuledepolymerization,exhibitinganticanceractivity.
| Purity | ≥95% |
|---|---|
| Formula | C45H53NO14 |
| FormulaWt. | 831.9 |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| MSDS | T0118MSDSPDF |
|---|---|
| InfoSheet | T0118InfoSheetPDF |
LiY,QinF,WangSM,etal.ChemicalstudiesonTaxuscanadensis.ChemBiodivers.2013Oct;10(10):1729-53.PMID:24130020.
OshigeM,TakenouchiM,KatoY,etal.TaxolderivativesareselectiveinhibitorsofDNApolymerasealpha.BioorgMedChem.2004May15;12(10):2597-601.PMID:15110841.
PandeyRC,YankovLK,PoulevA,etal.SynthesisandseparationofpotentialanticanceractivedihalocephalomanninediastereomersfromextractsofTaxusyunnanensis.JNatProd.1998Jan;61(1):57-63.PMID:9461653.