SN-38isacamptothecinderivative.Camptothecinisaquinolonealkaloidprecursorofirinotecan;itisoriginallyfoundinCamptotheca.Camptothecinexhibitsanticancerchemotherapeuticactivity,inhibitingtopoisomeraseIandinducingdouble-strandedDNAbreaks.Camptothecinisextremelycytotoxicandonlyitsderivativesareclinicallyusedaschemotherapeutics.
| CasNo. | 86639-52-3 |
|---|---|
| Purity | ≥98% |
| Formula | C22H20N2O5 |
| FormulaWt. | 392.40 |
| ChemicalName | 4,11-diethyl-4,9-dihydroxy-1H-Pyrano[3",4":6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione |
| Synonym | SN-38;7-ethyl-10-hydroxy-CPT |
| MeltingPoint | 228-235°C |
| Appearance | Lightyellowcrystallizedpowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| MSDS | C0154MSDSPDF |
|---|---|
| InfoSheet | C0154InfoSheetPDF |
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