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当前位置: 首页 > 产品中心 > clinical_research > LKT/VINPOCETINE/V3455/100 mg
商品详细LKT/VINPOCETINE/V3455/100 mg
LKT/VINPOCETINE/V3455/100 mg
LKT/VINPOCETINE/V3455/100 mg
商品编号: V3455-100mg
品牌: lktlabs
市场价: ¥6240.00
美元价: 3744.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • ProductInfo
  • ShippingandStorage
  • Downloads
  • References

Description

Vinpocetineisasyntheticanalogueofthealkaloidapovincamine,whichisisolatedfromthelesserperiwinkleplant.Ithasbeenshowntoinhibitlipopolysaccharide-inducedlunginflammationinmicebytargetingnuclearfactorkappaBactivation.FurThermore,itisknowntobeasafenootropicagentandiscommonlyusedtoenhancememoryandtotreatvariousneurologicaldiseases.

ProductInfo

CasNo.

42971-09-5

Purity

≥98%

Formula

C22H26N2O2

FormulaWt.

350.46

IUPACName

Ethyl(3α,16α)-eburnamenine-14-carboxylate

MeltingPoint

147-149°C

Solubility

SolubleinDMSO(5mg/ml),ethanol(15mg/ml)andDMF(3mg/m).

Appearance

Whitepowder

ShippingandStorage

StoreTemp

Ambient

ShipTemp

Ambient

Downloads

InfoSheet

V3455InfoSheetPDF

References

HagiwaraM,EndoT,HidakaH.Effectsofvinpocetineoncyclicnucleotidemetabolisminvascularsmoothmuscle.BiochemPharmacol.1984Feb1;33(3):453-7.PMID:6322804

MolnárP1,ErdöSL.Vinpocetineisaspotentasphenytointoblockvoltage-gatedNa+channelsinratcorticalneurons.EurJPharmacol.1995Feb6;273(3):303-6.PMID:7737339

GómezCD1,BuijsRM,SitgesM.Theanti-seizuredrugsvinpocetineandcarbamazepine,butnotvalproicacid,reduceinflammatoryIL-1βandTNF-αexpressioninrathippocampus.JNeuRochem.2014Sep;130(6):770-9.doi:10.1111/jnc.12784.Epub2014Jun27.PMID:24903676

WangH1,ZhangK2,ZhaoL3,TangJ3,GaoL3,WeiZ3.Anti-inflammatoryeffectsofvinpocetineonthefunctionalexpressionofnuclearfactor-kappaBandtumornecrosisfactor-alphainaratmodelofcerebralischemia-reperfusioninjury.NeurosciLett.2014Apr30;566:247-51.doi:10.1016/j.neulet.2014.02.045.Epub2014Mar2.PMID:24598438

ZhaoYY1,YuJZ,LiQY,MaCG,LuCZ,XiaoBG.TSPO-specificligandvinpocetineexertsaneuroprotectiveeffectbysuppressingmicroglialinflammation.NeuronGliaBiol.2011May;7(2-4):187-97.doi:10.1017/S1740925X12000129.Epub2012Jul6.PMID:22874716

Ruiz-MiyazawaKW,Pinho-RibeiroFA,ZarpelonAC,etal.Vinpocetinereduceslipopolysaccharide-inducedinflammatorypainandneutrophilrecruitmentinmicebytargetingoxidativestress,cytokines,andNF-kB.ChemBiolInteract.2015Jul25;237:9-17.PMID:25980587

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂