LKT/U03B1-生育三烯酚/T5608/10 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/U03B1-生育三烯酚/T5608/10 mg

LKT/U03B1-生育三烯酚/T5608/10 mg

商品编号： T5608-10mg

品牌： lktlabs

市场价： ¥5240.00

美元价： 3144.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDT5608

CasNo.58864-81-6

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Tocotrienolscontainanarenering,achromanolring,andanisoprenoidtail;alltocotrienolcompoundscontainamethylgrouponC8ofthearenering.α-Tocotrienolcontainstwoadditionalmethylgroupsarrangedaroundthearenering,positionedparaandorthotoC8.TocotrienolsaremembersofthevitaminEfamily,typicallyfoundinvegetableoils,nuts,andgrains.Alltocotrienolsexhibitstrongantioxidative,anti-angiogenic,anticancer,andanti-hyperlipidemicqualities,althoughα-Tocotrienoldisplaysthestrongestantioxidativecapacity.Tocopherols,commonsubstituentsofover-the-countervitaminEsupplements,interferewithtocotrienolactivityandshowweakerantioxidativeeffects.TocotrienolsexhibitsignificantrADIcalrecyclingABIlitiesincellularmodelsoflipidperoxidationandoxidativedamageandsuppressHMG-CoAreductaseactivity.Invitro,thesecompoundsinduceapoptosisthroughinhibitionofId1,EGFR,andNF-κB;theyalsoinhibitvesselformationandproliferationinaorticendothelialcells.

ProductInfo

CasNo.	58864-81-6
Purity	≥98%
Formula	C₂₉H₄₄O₂
FormulaWt.	424.66
IUPACName	(2R)-2,5,7,8-tetramethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl]-3,4-dihydrochromen-6-ol
Synonym	alpha-tocotrienol
Solubility	Solubleinethanol,hexanes,DMSO,DMF
Appearance	yellowliquid

ShippingandStorage

StoreTemp	-20°C
ShipTemp	Ambient

Downloads

MSDS	T5608MSDSPDF
InfoSheet	T5608InfoSheetPDF

References

YapWN,ChangPN,HanHY,etal.Gamma-tocotrienolsuppressesprostatecancercellproliferationandinvasionthroughmultiple-signallingpathways.BrJCancer.2008Dec2;99(11):1832-41.PMID:19002171.

SenCK,KhannaS,RoyS.Tocotrienols:VitaminEbeyondtocopherols.LifeSci.2006Mar27;78(18):2088-98.PMID:16458936.

InokuchiH,HirokaneH,TsuzukiT,etal.Anti-angiogenicactivityoftocotrienol.BiosciBiotechnolBiochem.2003Jul;67(7):1623-7.PMID:12913317.

ParkerRA,PearceBC,ClarkRW,etal.Tocotrienolsregulatecholesterolproductioninmammaliancellsbypost-transcriptionalsuppressionof3-hydroxy-3-methylglutaryl-coenzymeAreductase.JBiolChem.1993May25;268(15):11230-8.PMID:8388388.

SerbinovaE,KaganV,HanD,etal.Freeradicalrecyclingandintramembranemobilityintheantioxidantpropertiesofalpha-tocopherolandalpha-tocotrienol.FreeRadicBiolMed.1991;10(5):263-75.PMID:1649783.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂