Description
β-Casomorphinisapeptidefragmentofcaseinthatexhibitsantioxidativeandanti-fibroticactivities.Invivo,β-casomorphinimproveshighglucose-inducedchangesinoxidativeenzymesecretionandactivity.β-CasomorphinalsodecreasesurinaryglucoseandproteinlevelsaswellasserumcreatineandTGF-β1inanimalmodelsofdiabetes,preventingrenalinterstitialfibrosis.
References
ZhangW,MiaoJ,WangS,etal.Theprotectiveeffectsofbeta-casomorphin-7againstglucose-inducedrenaloxidativestressinvivoandvitro.PLoSOne.2013May3;8(5):e63472.PMID:23658831.
ZhangW,MiaoJ,MaC,etal.β-Casomorphin-7attenuatesthedevelopmentofnephropathyintypeIdiabetesviainhibitionofepithelial-mesenchymaltransitionofrenaltubularepithelialcells.Peptides.2012Aug;36(2):186-91.PMID:22687367.