Description
γ-Linolenicacid(GLA)isanomega-6fattyacidtypicallyfoundinvegetableoilsthatexhibitsantithrombotic,anti-inflammatory,andanti-atheroscleroticproperties.GLAisaprecursortoprostaglandinE1andeicosapentaenoicacid.ThiscompoundregulatesinsulinsecretionthroughitsnaturalagoNISTactivityatperoxisomeproliferator-activatedreceptors(PPARs);itinhibitsdiabetesmellitus-inducedalbuminuriaandincreasesinMCP-1.GLAmayalsohaveanticanceractivity,asitaltersgenerationofROS,decreasesproductionofTNF-α,andinducesapoptosisinleukemiacells.
References
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