Description
Atrialnatriureticpeptide(ANP)isacardiomodulatorypeptidethatbindsthenatriureticpeptidereceptortypeA(NPR-A),increasinglevelsofcGMPandactivatingcGMP-dependentkinases.ANPexhibitsvasodilatory/hypotensive,diuretic,andnatriureticactivities,increasingperfusionanddecreasingbloodpressureinseveralmodels.ANPmayalsoexhibitanticancerbenefit,targetingtheRas-MEK-ERKsignalingpathway.