Description
Adrenomedullinisanendogenouspeptidehormoneinvolvedingrowthanddifferentiationofstemcells.Thispeptideexhibitsvasodilatory,natriuretic,andcardioprotectiveactivities.Adrenomedullindecreasesbloodpressureandincreasesneovascularization.Thispeptidebindsmicrotubule-associatedproteinsintheCytoskeletonandalsoactivatesCLR-RAMPreceptors,regulatingvasculartoneandcardiovasculardevelopment.
References
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ShindoT,SakuraiT,KamiyoshiA,etal.RegulationofadrenomedullinanditsfamilypeptidebyRAMPsystem--lessonsfromgeneticallyengineeredmice.CurrProteinPeptSci.2013Aug;14(5):347-57.PMID:23745699.
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