LKT/ALLOPURINOL/A4445/5 g-免疫在线蚂蚁淘旗下平台

商品详细LKT/ALLOPURINOL/A4445/5 g

LKT/ALLOPURINOL/A4445/5 g

商品编号： A4445-5g

品牌： lktlabs

市场价： ¥580.00

美元价： 348.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDA4445

CasNo.315-30-0

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Allopurinolisapurineanalogthatmimicshypoxanthine,inhibitingxanthineoxidase;itisclinicallyusedtotreatdiseasesofhyperuricemia,suchasgout.Allopurinolexhibitsanti-inflammatory,nephroprotective,antinociceptive,antioxidative,anti-fibrotic,andcardioprotectiveactivities.Inanimalmodelsofrenalischemia,allopurinoldecreasesproductionofinflammatorycytokines.Inotheranimalmodels,allopurinoldecreasesoxidativestress,suppressesatrialfibrosis,andpreventsatrialfibrillation.Additionally,thiscompoundalsodecreasesnociceptioninanimalmodelsofthermalandchemicalpain,likelyduetoincreasinglevelsofhypoxanthineandxanthine,whicharemetabolizeddownstreamtoformadenosine.

ProductInfo

CasNo.	315-30-0
Purity	≥98%
Formula	C₅H₄N₄O
FormulaWt.	136.11
ChemicalName	1,5-Dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
IUPACName	1,2-dihydropyrazolo[3,4-d]pyrimidin-4-one
Synonym	Adenock;Apurol;Allozym;Apurin;Bloxanth;Embarin;Gichtex;Ketanrift;Lysuron;Urosin;Zyloric
MeltingPoint	>350°C
Solubility	SolubleinMethanolandDMSO.Slightlysolubleinethanol(0.30mg/ml)andwater(0.48mg/ml).
Appearance	WhiteCrystalPowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

MSDS	A4445MSDSPDF
InfoSheet	A4445InfoSheetPDF

References

Prieto-MoureB,Carabén-RedañoA,Aliena-ValeroA,etal.Allopurinolinrenalischemia.JInvestSurg.2014Oct;27(5):304-16.PMID:24914485.

EssawySS,ElbazAA.Roleofadenosinereceptorsintheanti-nociceptiveeffectsofallopurinolinmice.EurRevMedPharmacolSci.2013Jul;17(14):1857-63.PMID:23877847.

SakabeM,FujikiA,SakamotoT,etal.Xanthineoxidaseinhibitionpreventsatrialfibrillationinacaninemodelofatrialpacing-inducedleftventriculardysfunction.JCardiovascElectrophysiol.2012Oct;23(10):1130-5.PMID:22587612.

PacherP,NivorozhkinA,SzabóC.Therapeuticeffectsofxanthineoxidaseinhibitors:renaissancehalfacenturyafterthediscoveryofallopurinol.PharmacolRev.2006Mar;58(1):87-114.PMID:16507884.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂