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LKT/ANGIOTENSIN CONVERTING ENZYME INHIBITOR PEPTIDE/A5273/10 mg
Thispeptideisalsoknownasbradykinin-potentiatingpeptide9a;itexhibitsvasodilatoryandantihypertensiveactivity.Thispeptideinhibitsangiotensin-convertingenzyme(ACE)invivo,decreasingbloodpressure.Thispeptidealsoinhibitshydrolysisofbradykininandinactivationofleutinizinghormone-releasinghormone(LHRH).
| Purity | ≥95% |
|---|---|
| Formula | C53H77N14O12 |
| FormulaWt. | 1102.29 |
| Synonym | ACEinhibitorpeptide |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | A5273InfoSheetPDF |
|---|
MartinsAR,CaldoH,CoelhoHL,etal.Screeningforrabbitbrainneuropeptide-metabolizingpeptidases.InhibitionofendopeptidaseBbybradykininpotentiatingpeptide9a(SQ20881).JNeuRochem.1980Jan;34(1):100-7.PMID:6161209.
OparilS,KoernerT,O"DonoghueJK.MechanismofangiotensinIconvertingenzymeinhibitionbySQ20,881(lessthanGlu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro)invivo.Furtherevidenceforextrapulmonaryconversion.Hypertension.1979Jan-Feb;1(1):13-22.PMID:232489.
VollmerRR,BoccagnoJA,HarrisDN,etal.Hypotensioninducedbyinhibitionofangiotensin-convertingenzymeinpentobarbital-anesthetizeddogs.EurJPharmacol.1978Sep1;51(1):39-45.PMID:212276.
