Description
Argatroban is an antithrombotic/anticoagulant compound that inhibits thrombin. Argatroban is clinically used to treat thrombosis and acute coronary syndrome.
Argatroban is an antithrombotic/anticoagulant compound that inhibits thrombin. Argatroban is clinically used to treat thrombosis and acute coronary syndrome.
Cas No. | 74863-84-6 |
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Purity | ≥98% |
Formula | C23H36N6O5S |
Formula Wt. | 508.64 |
Chemical Name | (2R,4R)-4-Methyl-1-((S)-N(sup2)-(((RS)-1,2,3,4- tetrahydro-3-methyl-8-quinolyl)sulfonyl)arginyl)- pipecolic acid |
IUPAC Name | (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]pentanoyl]-4-methylpiperidine-2-carboxylic acid |
Synonym | Argatrobanum |
Melting Point | 188-191°C |
Solubility | Soluble in ethanol. |
Appearance | White Crystalline Powder |
Store Temp | Ambient |
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Ship Temp | Ambient |
MSDS | A6823 MSDS PDF |
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Info Sheet | A6823 Info Sheet PDF |
Tardy-Poncet B, Combe M, Piot M, et al. Effects of argatroban, danaparoid, and fondaparinux on trombin generation in heparin-induced thrombocytopenia. Thromb Haemost. 2013 Mar;109(3):504-9. PMID: 23328916.
Cruz-González I, López-Jiménez R, Perez-Rivera A, et al. Pharmacokinetic evaluation of argatroban for the treatment of acute coronary syndrome. Expert Opin Drug Metab Toxicol. 2012 Nov;8(11):1483-93. PMID: 22970706.