Description
Argatroban is an antithrombotic/anticoagulant compound that inhibits thrombin. Argatroban is clinically used to treat thrombosis and acute coronary syndrome.
Argatroban is an antithrombotic/anticoagulant compound that inhibits thrombin. Argatroban is clinically used to treat thrombosis and acute coronary syndrome.
| Cas No. | 74863-84-6 |
|---|---|
| Purity | ≥98% |
| Formula | C23H36N6O5S |
| Formula Wt. | 508.64 |
| Chemical Name | (2R,4R)-4-Methyl-1-((S)-N(sup2)-(((RS)-1,2,3,4- tetrahydro-3-methyl-8-quinolyl)sulfonyl)arginyl)- pipecolic acid |
| IUPAC Name | (2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]pentanoyl]-4-methylpiperidine-2-carboxylic acid |
| Synonym | Argatrobanum |
| Melting Point | 188-191°C |
| Solubility | Soluble in ethanol. |
| Appearance | White Crystalline Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | A6823 MSDS PDF |
|---|---|
| Info Sheet | A6823 Info Sheet PDF |
Tardy-Poncet B, Combe M, Piot M, et al. Effects of argatroban, danaparoid, and fondaparinux on trombin generation in heparin-induced thrombocytopenia. Thromb Haemost. 2013 Mar;109(3):504-9. PMID: 23328916.
Cruz-González I, López-Jiménez R, Perez-Rivera A, et al. Pharmacokinetic evaluation of argatroban for the treatment of acute coronary syndrome. Expert Opin Drug Metab Toxicol. 2012 Nov;8(11):1483-93. PMID: 22970706.