LKT/ASPEROSAPONIN VI/A7461/10 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/ASPEROSAPONIN VI/A7461/10 mg

LKT/ASPEROSAPONIN VI/A7461/10 mg

商品编号： A7461-10mg

品牌： lktlabs

市场价： ¥1340.00

美元价： 804.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDA7461

CasNo.39524-08-8

Purity≥98%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

AsperosaponinVIisatriterpenesaponinfoundintheDipsacusasperplant.AsperosaponinVIdisplayscardioprotectiveandantioxidativeactivities.Inanimalmodels,thiscompoundprotectstheheartfromischemicinjurybydecreasinglevelsoflactatedehydrogenase,creatinekinase,glutamicoxalacetictransaminase,andcardiactroponinT,andincreasinglevelsofrADIcalscavengingenzymessuchasglutathioneperoxidaseandsuperoxidedismutase.AsperosaponinVIalsoinhibitsapoptosisinhypoxiccardiacmyocytes,increasingtheBcl-2/Baxratioanddecreasingcaspase-3expression.Inananimalmodelofcardiacfibrosis,thiscompoundimprovesleftventriclesystolicpressureandleftventricleend-diastolicpressurebydecreasingexpressionofpro-inflammatorycytokinesIL-6andTNF-α.

ProductInfo

CasNo.	39524-08-8
Purity	≥98%
Formula	C₄₇H₇₆O₁₈
FormulaWt.	929.10
IUPACName	[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl](6aS,9R)-9-(hydroxymethyl)-2,2,6a,6b,9,12a-hexamethyl-10-[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
Synonym	AkebiaSaponinD
Appearance	WhitePowder

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

MSDS	A7461MSDSPDF
InfoSheet	A7461InfoSheetPDF

References

LiC,GaoY,TianJ,etal.Long-termoralAsperosaponinVIattenuatescardiacdysfunction,myocardialfibrosisinaratmodelofchronicmyocardialinfarction.FoodChemToxicol.2012May;50(5):1432-8.PMID:22343037.

LiC,TianJ,LiG,etal.AsperosaponinVIprotectscardiacmyocytesfromhypoxia-inducedapoptosisviaactivationofthePI3K/AktandCREBpathways.EurJPharmacol.2010Dec15;649(1-3):100-7.PMID:20863824.

LiC,LiuZ,TianJ,etal.ProtectiverolesofAsperosaponinVI,atriterpenesaponinisolatedfromDipsacusasperWallonacutemyocardialinfarctioninrats.EurJPharmacol.2010Feb10;627(1-3):235-41.PMID:19909736.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂