Description
AtriopeptinIIisananalogofatrialnatriureticpeptide(ANP)thatexhibitsvasodilatory/hypotensiveandanxiolyticactivities.LikeotherANPanalogs,atriopeptinIIdecreasesbloodpressure.Thispeptidealsoexhibitsanxiety-loweringbenefitinanimalsundergoingtestingintheelevatedplusmaze.
References
StröhleA,JahnH,MontkowskiA,etal.CentralandperipheraladmiNISTrationofatriopeptinisanxiolyticinrats.Neuroendocrinology.1997Mar;65(3):210-5.PMID:9088002.
PradaJA,RossR,ClarkKE.Effectofatrialnatriureticpeptideandothervasoactivecompoundsontheuterinevascularbedofthenonpregnantsheep.ProcSocExpBiolMed.1992Dec;201(3):261-6.PMID:1438342.