Sotalolisanon-selectiveinhibitorofβ-adrenergicreceptorsthatalsoinhibitsNa+andK+channels.SotalolactsasaclassIIIanti-arrhythmicdrugthatalsoexhibitsanti-fibrillatoryactivity.Sotalolisusedclinicallytotreatventricularfibrillationandventriculartachycardia.Invitroandinvivo,sotalolprolongsactionpotentialduration,QTandPRintervals,andincreasestheeffectiverefractoryperiod.
| CasNo. | 959-24-0 |
|---|---|
| Purity | ≥98% |
| Formula | C12H20N2O3S•HCl |
| FormulaWt. | 308.82 |
| IUPACName | N-[4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl]methanesulfonamide;hydrochloride |
| MeltingPoint | 206.5-207°C |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | S5976MSDSPDF |
|---|---|
| InfoSheet | S5976InfoSheetPDF |
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