Vasoactiveintestinalpeptide(VIP)isanendogenouspeptidehormonethatexhibitsbronchodilatory,vasodilatory,andimmunomodulatoryactivities.VIPincreaseslevelsofIL-10,Foxp3,andTGF-βinvivoandpreventsLPS-inducedexpressionofIL-6andMCP-1invitro.VIPappearstoplayasignificantroleinrespiratoryinflammation.
| CasNo. | 40077-57-4 |
|---|---|
| Purity | ≥95% |
| Formula | C57H70N12O9S |
| FormulaWt. | 3325.7 |
| Appearance | WhitetoOff-whitePowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | V0273InfoSheetPDF |
|---|
HaukV,AzzamS,CaloG,etal.VasoactiveintestinalPeptideinducesanimmunosuppressantmicroenvironmentinthematernal-fetalinterfaceofnon-obesediabeticmiceandimprovesearlypregnancyoutcome.AmJReprodImmunol.2014Feb;71(2):120-30.PMID:24405265.
FraccaroliL,GrassoE,HaukV,etal.ContributionofVasoactiveIntestinalPeptidetoImmuneHomeostasisinTrophoblast-MaternalLeukocyteInteractionunderLPSStimulation.Neuroimmunomodulation.2014;21(1):21-30.PMID:24135863.
MathioudakisA,Chatzimavridou-GrigoriadouV,EvangelopoulouE,etal.VasoactiveintestinalPeptideinhaledagoNISTs:potentialroleinrespiratorytherapeutics.Hippokratia.2013Jan;17(1):12-6.PMID:23935337.
