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商品详细LKT/尿皮质素,人/U6854/1毫克
LKT/尿皮质素,人/U6854/1毫克
LKT/尿皮质素,人/U6854/1毫克
商品编号: U6854-1mg
品牌: lktlabs
市场价: ¥10700.00
美元价: 6420.00
产地: 美国(厂家直采)
公司:
产品分类: 临床研究
公司分类: clinical_research
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
  • Description
  • Product Info
  • Shipping and Storage
  • Downloads
  • References

Description

Urocortin is an endogenous peptide ligand and member of the corticotropin-releasing factor (CRF) family; it binds and activates CRF type 1 and 2 receptors. Urocortin modulates stress responses and exhibits anorexigenic, anxiogenic, and positive inotropic effects across a wide variety of in vivo models. Urocortin is primarily expressed in the heart. Urocortin exerts many effects on signaling of the hypothalamic-pituitary-adrenal (HPA) axis, including increasing corticosterone and adrenocorticotropic hormone (corticotropin) levels.

Product Info

Cas No.

171543-83-2

Purity

≥98%

Formula

C204H337N63O64

Formula Wt.

4696.3

Solubility

Insoluble in water.

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

Info Sheet

U6854 Info Sheet PDF

References

Bagosi Z, Csabafi K, Palotai M, et al. The effect of urocortin I on the hypothalamic ACTH secretagogues and its impact on the hypothalamic-pituitary-adrenal axis. Neuropeptides. 2013 Nov 21. pii: S0143-4179(13)00100-5. PMID: 24331779.

Dono LM, Currie PJ. The cannabinoid receptor CB1 inverse agonist AM251 potentiates the anxiogenic activity of urocortin I in the basolateral amygdala. Neuropharmacology. 2012 Jan;62(1):192-9. PMID: 21736884.

Currie PJ, Coiro CD, Duenas R, et al. Urocortin I inhibits the effects of ghrelin and neuropeptide Y on feeding and energy substrate utilization. Brain Res. 2011 Apr 18;1385:127-34. PMID: 21303672.

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

品牌介绍
LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 试剂