7,8-Dihydrokawain is a kavalactone originally found in Piper methysticum (kava plant) that exhibits neuroprotective activity. 7,8-Dihydrokawain activates Nrf2 in neurons and astroglia, protecting against amyloid-β (Aβ)-induced neurotoxicity.
| Cas No. | 587-63-3 |
|---|---|
| Purity | ≥98% |
| Formula | C14H16O3 |
| Formula Wt. | 232.28 |
| IUPAC Name | 4-methoxy-2-(2-phenylethyl)-2,3-dihydropyran-6-one |
| Synonym | DHK; Dihydrokawain; Marindinin |
| Melting Point | 56-60°C |
| Solubility | Soluble in DMSO and methanol. |
| Appearance | White/Off White Crystalline Powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| MSDS | D3229 MSDS PDF |
|---|---|
| Info Sheet | D3229 Info Sheet PDF |
Xuan TD, Elzaawely AA, Fukuta M, et al. Herbicidal and Fungicidal Activities of Lactones in Kava (Piper methysticum). J Agric Food Chem. 2006 Feb 8;54(3):720-5. PMID: 16448174.
