Description
This peptide shows mixed effects on direct food intake in vivo and may display anorexigenic activity. This peptide inhibits hormonal and gastric secretory responses, decreasing secretion of gastrin or other pancreatic hormones in response to feeding and similar stimuli.
References
Blavet N, DeFeudis FV, Clostre F. Lack of effect of the peptide pyro-Glu-His-Gly-OH on food consumption in mice and rats. Gen Pharmacol. 1982;13(2):173-6. PMID: 6807743.
Coy D, Jaworek J, Konturek SJ, et al. Effects of anorexigenic peptide on gastric and pancreatic secretion. J Physiol. 1981 May;314:225-35. PMID: 7031225.