Betamethasone is a glucocorticoid receptor agonist that exhibits anti-inflammatory, immunosuppressive, and anti-ulcerative activities. Betamethasone is clinically used to treat skin irritations such as psoriasis and to accelerate preterm fetal lung development.
| Cas No. | 151-73-5 |
|---|---|
| Purity | ≥98% |
| Formula | C22H28FNa2O8P |
| Formula Wt. | 516.40 |
| Chemical Name | (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 21-phosphate disodium salt |
| IUPAC Name | disodium;[2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] phosphate |
| Synonym | Betamethasone 21-Phosphate disodium salt; Bentelan; Betnesol; Celestan; Vista-Methasone |
| Solubility | Soluble in water (500 mg/mL). Slightly soluble in alcohol (2 mg/mL). Insoluble in chloroform. |
| Appearance | White to off white powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | B1878 MSDS PDF |
|---|---|
| Info Sheet | B1878 Info Sheet PDF |
Shepherd J, Taheri A, Feldman SR. Once-daily topical treatment for psoriasis: calcipotriene + betamethasone two-compound topical formulation. Clin Cosmet Investig Dermatol. 2013 Dec 19;7:19-22. PMID: 24379688.
Waffarn F, Davis EP. Effects of antenatal corticosteroids on the hypothalamic-pituitary-adrenocortical axis of the fetus and newborn: experimental findings and clinical considerations. Am J Obstet Gynecol. 2012 Dec;207(6):446-54. PMID: 22840973.
