Biotinisawater-solubleBvitamin(vitaminB7)thatmaybefoundinmanyfoodsbutisalsoadmiNISTeredasadietarysupplement.Biotinisacoenzymeinvolvedinthesynthesisoffattyacids,isoleucine,andvaline;italsoplaysaroleingluconeogenesis.Biotinmaybefoundattachedtolysineresiduesonhistones,modulatinggeneticregulation.Biotinconjugatesareusedtostudythebindingofsmall,bioactivemoleculestoendogenoussubstrates.
| CasNo. | 58-85-5 |
|---|---|
| Purity | ≥98% |
| Formula | C10H16N2O3S |
| FormulaWt. | 244.31 |
| ChemicalName | Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoicacid |
| IUPACName | 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoicacid |
| Synonym | Biodermatin;CoenzymeR;Vitamin H |
| MeltingPoint | 232-233°C |
| Solubility | Solubleinwater(0.2 mg/mL).Verysolubleinhotwateranddilutealkali.Insolubleincommonorganicsolvents.DMSOto49mg/mL.2MNaOHto50mg/mL. |
| Appearance | AWhiteoroff-WhiteCrystallinePowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | B3278MSDSPDF |
|---|---|
| InfoSheet | B3278InfoSheetPDF |
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ZempleniJ,WijeratneSS,HassanYI.Biotin.Biofactors.2009Jan-Feb;35(1):36-46.PMID:19319844.
