LKT/CALCITRIOL/C0145/1 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/CALCITRIOL/C0145/1 mg

LKT/CALCITRIOL/C0145/1 mg

商品编号： C0145-1mg

品牌： lktlabs

市场价： ¥13940.00

美元价： 8364.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDC0145

CasNo.32222-06-3

Purity≥97%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

CalcitriolistheactiveformofvitaminDthatbindstothevitaminDreceptors(VDR),increasingabsorptionofdietaryCa2+.CalcitriolisproducedinthekidneyfromprodrugformsofvitaminDsuchascholecalciferol.Calcitrioliscommerciallyusedindietarysupplementstopreventosteoporosis;itexhibitsanti-osteoporotic,immunomodulatory,anti-inflammatory,anti-diabetic,anticancer,andchemopreventiveactivities.Inbasalcellcarcinomacells,calcitrioldecreaseshedgehog(Hh)signaling,suppressingcancerprogression.Inothermodels,calcitriolstimulatesdifferentiationofskincellsandinhibitsskincancercellproliferationandtumorformation.Additionally,thiscompounddecreasesactivationoftoll-likereceptors(TLRs),protectingagainstthedevelopmentoftypeIdiabetes.

ProductInfo

CasNo.	32222-06-3
Purity	≥97%
Formula	C₂₇H₄₄O₃
FormulaWt.	416.64
ChemicalName	(1α,3β,5Z,7E)-9,10-Secocholesta-5,710(19)-triene-1,3,25-triol
IUPACName	5-[2-[1-(6-hydroxy-6-methylheptan-2-yl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
Synonym	1α,25-DihydroxyvitaminD3
MeltingPoint	111-115°C
Solubility	Slightlysolubleinethanol,ethylacetate.SolubleinDMSO
Appearance	WhiteSolid

ShippingandStorage

StoreTemp	-80°C
ShipTemp	DryIce

Downloads

MSDS	C0145MSDSPDF
InfoSheet	C0145InfoSheetPDF
Brochures	HedgehogSignalingFlyer

References

AlbertB,HahnH.InteractionofhedgehogandvitaminDsignalingpathwaysinbasalcellcarcinomas.AdvExpMedBiol.2014;810:329-41.PMID:25207374.

BikleDD.ThevitaminDreceptor:atumorsuppressorinskin.AdvExpMedBiol.2014;810:282-302.PMID:25207372.

AdamczakDM,NowakJK,FrydrychowiczM,etal.TheroleofToll-likereceptorsandvitaminDindiabetesmellitustype1--areview.ScandJImmunol.2014Aug;80(2):75-84.PMID:24845558.

VojinovicJ.VitaminDreceptoragoNISTs"anti-inflammatoryproperties.AnnNYAcadSci.2014May;1317:47-56.PMID:24754474.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂