Chromium picolinate is clinically used to decrease fasting blood glucose and insulin levels. Chromium picolinate exhibits anti-hyperlipidemic, cardioprotective, and anti-diabetic activities. In high-fat diet-fed rats, chromium picolinate decreases plasma lipid levels and platelet aggregation. In spontaneously hypertensive rats, this compound improves myocardial contractility, myocardial relaxation, and coronary blood flow after cardiac ischemia/reperfusion.
| Cas No. | 14639-25-9 |
|---|---|
| Purity | ≥98% |
| Formula | C18H12CrN3O6 |
| Formula Wt. | 418.30 |
| Chemical Name | Tris(2-pyridinecarboxylato-N1,O2)chromium |
| IUPAC Name | chromium(3+);pyridine-2-carboxylate |
| Synonym | Chromium(III) trispicolinate |
| Melting Point | Dec°mp°ses |
| Solubility | Soluble in 0.6 mM water (pH 7.0) or 2.0 mM chloroform. |
| Appearance | Amaranthine Crystalline Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | C2965 Info Sheet PDF |
|---|
Seif AA. Chromium picolinate inhibits cholesterol-induced stimulation of platelet aggregation in hypercholesterolemic rats. Ir J Med Sci. 2014 Mar 15. [Epub ahead of print]. PMID: 24633441.
Amooee S, Parsanezhad ME, Ravanbod Shirazi M, et al. Metformin versus chromium picolinate in clomiphene citrate-resistant patients with PCOs: A double-blind randomized clinical trial. Iran J Reprod Med. 2013 Aug;11(8):611-8. PMID: 24639797.
Abebe W, Liu JY, Wimborne H, et al. Effects of chromium picolinate on vascular reactivity and cardiac ischemia-reperfusion injury in spontaneously hypertensive rats. Pharmacol Rep. 2010 Jul-Aug;62(4):674-82. PMID: 20885007.
