LKT/D-LIMONENE/L3250/500 mL-免疫在线蚂蚁淘旗下平台

商品详细LKT/D-LIMONENE/L3250/500 mL

LKT/D-LIMONENE/L3250/500 mL

商品编号： L3250-500mL

品牌： lktlabs

市场价： ¥1600.00

美元价： 960.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

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商品介绍

ProductIDL3250

CasNo.5989-27-5

Purity≥96%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

D-LimoneneisaterpenefoundintherindofvariousspeciesofCitrus.D-Limoneneiscommerciallyusedasaflavorant,odorant,cleaningsolvent,andinsecticide;itexhibitsanti-inflammatory,antioxidative,hepatoprotective,anti-diabetic,anti-obesity,immunosuppressive,anticancerchemotherapeutic,chemopreventive,anti-metastatic,andanti-angiogenicactivities.D-Limoneneinhibitscellgrowth,inducesmitochondria-dependentapoptosis,andcausescellcyclearrestingastriccarcinomacells.Inotherinvitromodels,D-limoneneinhibitsVEGF,tubeformation,andmetastasis.Additionally,thiscompounddecreasesDMBA-inducedtumorformationandtumorburden,potentiallythroughdecreasingRas,Raf,andphosphorylatedERK1/2levels.Inotheranimalmodels,D-limoneneinducesphaseIIenzymeexpression,increasinglevelsofglutathione;italsodecreaseslevelsofKIM-1,Bun,creatinine,NO,iNOS,COX,andNF-κB,limitingdoxycycline-inducedrenaldamage.ThiscompoundalsodecreasesADIpocytesizeandlevelsofbloodglucose,LDL,andtriglycerides,increaseslevelsofHDL,activatesPPARαsignaling,andsuppressesLXR-βsignalinginvivo.D-LimoneneinhibitscytokineproductionbyCD4+andCD8+TcellsandinducesTcelldeathathighdoses.

ProductInfo

CasNo.	5989-27-5
Purity	≥96%
Formula	C₁₀H₁₆
FormulaWt.	136.23
ChemicalName	(+)-4-Isopropenyl-1-methylcyclohexene
IUPACName	(4R)-1-methyl-4-prop-1-en-2-ylcyclohexene
Synonym	(+)-Dipentene;(+)-Limonene;(+)-R-Limonene;(+)-α-Limonene
MeltingPoint	-40°C
Solubility	Insolubleinwater.
Appearance	Liquid

ShippingandStorage

StoreTemp	Ambient
ShipTemp	Ambient

Downloads

InfoSheet	L3250InfoSheetPDF

References

ZhangXZ,WangL,LiuDW,TangGY,ZhangHY.SynergisticInhibitoryEffectofBerberineandd-LimoneneonHumanGastricCarcinomaCellLineMGC803.JMedFood.2014Sep;17(9):955-62.PMID:25045784.

RehmanMU,TahirM,KhanAQ,etal.D-limonenesuppressesdoxorubicin-inducedoxidativestressandinflammationviarepressionofCOX-2,iNOS,andNFκBinkidneysofWistarrats.ExpBiolMed(Maywood).2014Apr;239(4):465-76.PMID:24586096.

JingL,ZhangY,FanS,etal.PreventiveandamelioratingeffectsofcitrusD-limoneneondyslipidemiaandhyperglycemiainmicewithhigh-fatdiet-inducedobesity.EurJPharmacol.2013Sep5;715(1-3):46-55.PMID:23838456.

LappasCM,LappasNT.D-LimonenemodulatesTlymphocyteactivityandviABIlity.CellImmunol.2012Sep;279(1):30-41.PMID:23059811.

ChaudharySC,SiddiquiMS,AtharM,etal.D-Limonenemodulatesinflammation,oxidativestressandRas-ERKpathwaytoinhibitmurineskintumOrigenesis.HumExpToxicol.2012Aug;31(8):798-811.PMID:22318307.

SunJ.D-Limonene:safetyandclinicalapplications.AlternMedRev.2007Sep;12(3):259-64.PMID:18072821.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂