LKT/SOMATOSTATIN-28 (1-12)/S5752/2 mg-免疫在线蚂蚁淘旗下平台

商品详细LKT/SOMATOSTATIN-28 (1-12)/S5752/2 mg

LKT/SOMATOSTATIN-28 (1-12)/S5752/2 mg

商品编号： S5752-2mg

品牌： lktlabs

市场价： ¥7300.00

美元价： 4380.00

产地：美国(厂家直采)

公司：

产品分类：临床研究

公司分类： clinical_research

联系Q Q： 3392242852

电话号码： 4000-520-616

电子邮箱： info@ebiomall.com

立即询价

商品介绍

ProductIDS5752

CasNo.81286-16-0

Purity≥95%

Description
ProductInfo
ShippingandStorage
Downloads
References

Description

Somatostatinisanendogenousneuropeptidehormonefoundinthebrainandpancreas.Somatostatinbindsseveralisoformsofthesomatostatinreceptor,exhibitinganxiolytic,antiepileptic/anticonvulsant,andanorexigenicactivities.Invivo,somatostatinimprovesperformanceinthelight/darkavoidancetest.Somatostatinalsosuppressesseizuresandpreventsthegenerationofseizures,potentiallythroughmodulationofGABAsignaling.Somatostatininducescelldeathunderhypoxic/ischemicconditions.Intumorcells,somatostatindisplayspro-apoptoticproperties,potentiallyinvolvingtheinhibitionofPI3K/Aktsignaling.SomatostatinalsolimitsfoodintakeandinhibitssecretionofinsulinandglucagonthroughalterationofGβγsignalingandP/Q-typeN-type,andL-typevoltage-gatedCa2+channelsignaling.

ProductInfo

CasNo.	81286-16-0
Purity	≥95%
Formula	C₄₉H₈₁N₁₇O₁₉S
FormulaWt.	1244.36
IUPACName	(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-4-amino-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]propanoyl]amino]-4-oxobutanoyl]amino]-3-hydroxypropanoyl]amino]-4-oxobutanoyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]pentanedioicacid

ShippingandStorage

StoreTemp	-20°C
ShipTemp	Ambient

Downloads

InfoSheet	S5752InfoSheetPDF

References

StummR.Somatostatinreceptorsst2reducesAktactivityandaggravateshypoxic/ischemicdeathincerebralcorticalneurons.Neuropharmacology.2014Feb;77:249-56.PMID:24157493.

TakahashiM,TakedaM,MatsumotoS.Somatostatinenhancestooth-pulp-evokedcervicaldorsalhornneuronalactivityintheratviainhibitionofGABAergicinterneurons.BrainResBull.2014Jan;100:76-83.PMID:24321530.

AlbrechtA,ThiereM,Bergado-AcostaJR,etal.CircADIanmodulationofanxiety:aroleforsomatostatinintheamygdala.PLoSOne.2013Dec20;8(12):e84668.PMID:24376834.

KovacS,WalkerMC.Neuropeptidesinepilepsy.Neuropeptides.2013Dec;47(6):467-75.PMID:24210141.

BeggDP,WoodsSC.Interactionsbetweenthecentralnervoussystemandpancreaticisletsecretions:ahistoricalperspective.AdvPhysiolEduc.2013Mar;37(1):53-60.PMID:23471249.

SchwetzTA,UstioneA,PistonDW.NeuropeptideYandsomatostatininhibitinsulinsecretionthroughdifferentmechanisms.AmJPhysiolEndocrinolMetab.2013Jan15;304(2):E211-21.PMID:23211512.

KaileyB,vandeBuntM,CheleyS,etal.SSTR2isthefunctionallydominantsomatostatinreceptorinhumanpancreaticβ-andα-cells.AmJPhysiolEndocrinolMetab.2012Nov1;303(9):E1107-16.PMID:22932785.

品牌介绍

LKT Labs LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。试剂