Stresscopin is a 2-amino acid peptide extension of urocortin III that includes a preceding T-K tag. Like urocortin III, stresscopin is a member of the corticotropin-releasing factor (CRF) family that binds to the CRF type 2 receptor (CRFR2). Stresscopin signaling results in suppression of food intake, delay of gastric emptying, hypotension/hypertension (depending on the model), and tachycardia.
| Cas No. | 352020-03-2 |
|---|---|
| Purity | ≥95% |
| Formula | C195H326N56O53S2 |
| Formula Wt. | 4367.24 |
| Appearance | White to off white powder |
| Store Temp | -20°C |
|---|---|
| Ship Temp | Ambient |
| Info Sheet | S7871 Info Sheet PDF |
|---|
Jin R, Li MZ, Bing YH, et al. Intracerebroventricular injection of stresscopin-related peptide enhances cardiovascular function in conscious rats. Regul Pept. 2013 Sep 10;186:7-11. PMID: 23850799.
Bagosi Z, Csabafi K, Palotai M, et al. The interaction of Urocortin II and Urocortin III with amygdalar and hypothalamic cotricotropin-releasing factor (CRF)--reflections on the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Neuropeptides. 2013 Oct;47(5):333-8. PMID: 23932308.
Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.
Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.
