Description
WS6isanactivatorofisletβcellproliferationthatalsostimulatesαcellproliferation.WS6displayspotentialanti-diabeticactivity,normalizingbloodglucoselevels.
WS6isanactivatorofisletβcellproliferationthatalsostimulatesαcellproliferation.WS6displayspotentialanti-diabeticactivity,normalizingbloodglucoselevels.
CasNo. | 1421227-53-3 |
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Purity | ≥98% |
Formula | C29H31F3N6O3 |
FormulaWt. | 568.60 |
IUPACName | N-(6-{4-[2-({4-[(4-Methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl}amino)-2-oxoethyl]phenoxy}-4-pyrimidinyl)cyclopropanecarboxamide |
StoreTemp | -20°C |
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ShipTemp | Ambient |
InfoSheet | W7201InfoSheetPDF |
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BoernerBP,GeorgeNM,MirSU,etal.WS6inducesbothalphaandbetacellproliferationwithoutaffectingdifferentiationorviABIlity.EndocrJ.2015;62(4):379-86.PMID:25739404.
ShenW,TremblayMS,DeshmukhVA,etal.Small-moleculeinducerofβcellproliferationidentifiedbyhigh-throughputscreening.JAmChemSoc.2013Feb6;135(5):1669-72.Erratumin:JAmChemSoc.2013Mar20;135(11):4573.PMID:23330637.