Description
Acyclovir is a guanosine nucleoside analog that exhibits antiviral activity. Acyclovir is clinically used to treat infections of the herpes simplex virus; it inhibits viral DNA polymerase and D-amino acid oxidase.
Acyclovir is a guanosine nucleoside analog that exhibits antiviral activity. Acyclovir is clinically used to treat infections of the herpes simplex virus; it inhibits viral DNA polymerase and D-amino acid oxidase.
| Cas No. | 59277-89-3 |
|---|---|
| Purity | ≥98% |
| Formula | C8H11N5O3 |
| Formula Wt. | 225.20 |
| Chemical Name | Acycloguanosine; Vipral; Zovirax |
| IUPAC Name | 2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one |
| Melting Point | 256.5-257°C |
| Solubility | MeOH, Poor solubility in water. |
| Appearance | White Crystalline Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | A1096 MSDS PDF |
|---|---|
| Info Sheet | A1096 Info Sheet PDF |
James SH, Prichard MN. Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance. Curr Opin Virol. 2014 Jul 15;8C:54-61. PMID: 25036916.
Katane M, Matsuda S, Saitoh Y, et al. The antiviral drug acyclovir is a slow-binding inhibitor of (D)-amino acid oxidase. Biochemistry. 2013 Aug 20;52(33):5665-74. PMID: 23859606.
Elion GB. Mechanism of action and selectivity of acyclovir. Am J Med. 1982 Jul 20;73(1A):7-13. PMID: 6285736.