Description
Alamethicin is a peptabiol peptide initially produced by species of Trichoderma. Alamethicin is an antimicrobial peptide (AMP) that disturbs the lipid layer of the cell membrane, aggregating and forming pores and causing cell lysis.
Alamethicin is a peptabiol peptide initially produced by species of Trichoderma. Alamethicin is an antimicrobial peptide (AMP) that disturbs the lipid layer of the cell membrane, aggregating and forming pores and causing cell lysis.
Cas No. | 27061-78-5 |
---|---|
Purity | ≥95% |
Formula | C92H150N22O25 |
Formula Wt. | 1964.4 |
Melting Point | 255-270°C |
Solubility | DMSO, Methanol (20 mg/ml), Ethanol (100 mg/ml) |
Appearance | Off white to beige powder |
Store Temp | 4°C |
---|---|
Ship Temp | Ambient |
MSDS | A4400 MSDS PDF |
---|---|
Info Sheet | A4400 Info Sheet PDF |
Krauson AJ, He J, Wimley WC. Determining the mechanism of membrane permeabilizing peptides: identification of potent, equilibrium pore-formers. Biochim Biophys Acta. 2012 Jul;1818(7):1625-32. PMID: 22365969.
Huang HW. Molecular mechanism of antimicrobial peptides: the origin of cooperativity. Biochim Biophys Acta. 2006 Sep;1758(9):1292-302. PMID: 16542637.