Description

Albendazole is a benzimidazole compound that exhibits anti-parasitic and anticancer chemotherapeutic activities. Albendazole displays anti-helminthic benefit in the treatment of worm infections in humans and animals. Albendazole also displays antimitotic properties, binding the colchicine site of tubulin and inhibiting microtubule polymerization. In cellular and animal models of colorectal cancer, albendazole induces G2/M phase cell cycle arrest and apoptosis and decreases tumor growth.