AmitrazisanagoNISTatα-adrenergicreceptorsthatdisplaysinsecticideactivity.Amitrazalsoinhibitsmonoamineoxidase(MAO)andsynthesisofprostaglandins.Additionally,amitrazmayactonoctopaminereceptors.Amitrazactsasanacaricideandiscommonlyusedinveterinaryprophylaxisagainstfleaandtickinfections.Amitrazmayinhibitβ-cellinsulinreleaseinmammals.
| CasNo. | 33089-61-1 |
|---|---|
| Purity | ≥97% |
| Formula | C19H23N3 |
| FormulaWt. | 293.41 |
| ChemicalName | N"-(2,4-Dimethylphenyl)-N-[[(2,4-dimethylphenyl)imino]methyl]-N-methylmethanimidamide |
| IUPACName | N"-(2,4-dimethylphenyl)-N-[(2,4-dimethylphenyl)iminomethyl]-N-methylmethanimidamide |
| Synonym | Aludex;Mitaban;Mitac;Taktic;Topline |
| MeltingPoint | 86-87°C |
| Solubility | Insolubleinwater.Solubleinxyleneandacetone. |
| Appearance | WhitetoYellowishPowder |
| StoreTemp | 4°C |
|---|---|
| ShipTemp | Ambient |
| MSDS | A5039MSDSPDF |
|---|---|
| InfoSheet | A5039InfoSheetPDF |
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ChenTH,HsuWH.Inhibitionofinsulinreleasebyaformamidinepesticideamitrazanditsmetabolitesinaratbeta-cellline:anactionmediatedbyalpha-2adrenoceptors,aGTP-bindingproteinandadecreaseincyclicAMP.JPharmacolExpTher.1994Dec;271(3):1240-5.PMID:7527851.
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