Amoxicillin is a β-lactam penicillin antibiotic that exhibits antibacterial efficacy against both gram positive and gram negative bacteria. Amoxicillin inhibits peptidoglycan polymerization through binding of penicillin binding proteins, inhibiting cell wall synthesis.
| Cas No. | 26787-78-0 |
|---|---|
| Purity | ≥98% |
| Formula | C16H19N3O5S |
| Formula Wt. | 365.41 |
| Chemical Name | (2S,5R,6R)-6-[[(2R)-amino(4-hydroxyphenyl)- acetyl]amino]-3,3-dimethyl-7-oxo-4-Thia-1-azabicyclo-[3.2.0]heptane-2-carboxylic acid |
| IUPAC Name | (2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| Synonym | Amoxycillin; Amolin; Amopenixin; Helvamox; Moxal; Pasetocin; AMPC |
| Melting Point | 194°C |
| Solubility | Soluble in water, DMSO, ethanol. |
| Appearance | White to off white powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | A5057 MSDS PDF |
|---|---|
| Info Sheet | A5057 Info Sheet PDF |
Astasov-Frauenhoffer M, Braissant O, Hauser-Gerspach I, et al. Microcalorimetric determination of the effects of amoxicillin, metronidazole, and their combination on in vitro biofilm. J Periodontol. 2014 Feb;85(2):349-57. PMID: 23594193.
Martin SI, Kaye KM. Beta-lactam antibiotics: newer formulations and newer agents. Infect Dis Clin North Am. 2004 Sep;18(3):603-19. PMID: 15308278.
Weber DJ, Tolkoff-Rubin NE, Rubin RH. Amoxicillin and potassium clavulanate: an antibiotic combination. Mechanism of action, pharmacokinetics, antimicrobial spectrum, clinical efficacy and adverse effects. Pharmacotherapy. 1984 May-Jun;4(3):122-36. PMID: 6739312.
