Aspartame is a dipeptide ester that is used as an artificial sweetener in commercial food production. Aspartame exhibits antibacterial efficacy against Porphyromonas, a periodontal pathogen. In vivo, aspartame also displays antinociceptive activity, increasing latency times in tail flick and paw lick assays.
| Cas No. | 22839-47-0 |
|---|---|
| Purity | ≥98% |
| Formula | C14H18N2O5 |
| Formula Wt. | 294.30 |
| Chemical Name | N-L-α-Aspartyl-L-phenylalanine 1-methyl ester |
| IUPAC Name | (3S)-3-amino-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid |
| Synonym | APM; Equal; NutraSweet; Sanecta |
| Melting Point | 246-247°C |
| Solubility | Slightly soluble in water. |
| Appearance | A White Powder |
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
| MSDS | A7462 MSDS PDF |
|---|---|
| Info Sheet | A7462 Info Sheet PDF |
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Rani S, Gupta MC. Evaluation and comparison of antinociceptive activity of aspartame with sucrose. Pharmacol Rep. 2012;64(2):293-8. PMID: 22661178.
Yagasaki M, Hashimoto S. Synthesis and application of dipeptides; current status and perspectives. Appl Microbiol Biotechnol. 2008 Nov;81(1):13-22. PMID: 18795289.
Butchko HH, Stargel WW, Comer CP, et al. Aspartame: review of safety. Regul Toxicol Pharmacol. 2002 Apr;35(2 Pt 2):S1-93. PMID: 12180494.
