Bactenecinisacathelicidin-derivedantimicrobialpeptide(AMP)foundinbovineneutrophils.Bactenecinexhibitsantibioticactivity,increasingmembranepermeABIlityandinhibitinggrowth.Bactenecinisaneffectiveantibacterialpeptide,displayingactivityagainstBurkholderia,Escherichia,Pseudomonas,Salmonella,Staphylococcus,andEnterobacter.
| CasNo. | 116229-36-8 |
|---|---|
| Purity | ≥95% |
| Formula | C63H118N24O13S2 |
| FormulaWt. | 1483.90 |
| IUPACName | 2-[[28-[[2-[[2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-13,22-di(butan-2-yl)-10,25-bis[3-(diaminomethylideneamino)propyl]-6,9,12,15,18,21,24,27-octaoxo-7,16,19-tri(propan-2-yl)-1,2-dithia-5,8,11,14,17,20,23,26-octazacyclononacosane-4-carbonyl]amino]-5-(diaminomethylideneamino)pentanoicacid |
| Synonym | Arg-leu-cyclo(cys-arg-ile-val-val-ile-arg-val-cys)-arg;Bac7 |
| Appearance | Whitetooffwhitepowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | B0108InfoSheetPDF |
|---|
MadhongsaK,PasanS,PhophetlebO,etal.AntimicrobialactionofthecyclicpeptidebactenecinonBurkholderiapseudomalleicorrelateswithefficientmembranepermeabilization.PLoSNeglTropDis.2013Jun13;7(6):e2267.PMID:23785532.
LeeJY,YangST,LeeSK,etal.Salt-resistanthomodimericbactenecin,acathelicidin-derivedantimicrobialpeptide.FEBSJ.2008Aug;275(15):3911-20.PMID:18616463.
WuM,HancockRE.Interactionofthecyclicantimicrobialcationicpeptidebactenecinwiththeouterandcytoplasmicmembrane.JBiolChem.1999Jan1;274(1):29-35.PMID:9867806.
