Belinostatisahistonedeacetylase(HDAC)inhibitorthatexhibitsantiviralandanticancerchemotherapeuticactivities.BelinostatisapprovedforuseinhumansinthetreatmentofTcelllymphomaandiscurrentlyinclinicaltrialsasapotentialtreatmentforotherleukemiasandlymphomas.Inpancreaticcancercells,belinostatinducesapoptosisinanAMPK-dependentmanner.Inothercellularmodels,thiscompounddecreasesHIVreleasefrommacrophagesbydegrADIngintracellularHIV.
| CasNo. | 414864-00-9 |
|---|---|
| Purity | ≥98% |
| Formula | C15H14N2O4S |
| FormulaWt. | 318.35 |
| Synonym | PXD101 |
| Appearance | Paleyellowpowder |
| StoreTemp | -20°C |
|---|---|
| ShipTemp | Ambient |
| InfoSheet | B1746InfoSheetPDF |
|---|
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