Benzydamineisanon-steroidalanti-inflammatorydrug(NSAID)thatalsoexhibitsanalgesic,anesthetic,andantibacterialactivities.Benzydamineisclinicallyusedtotreatmucositisandsorethroat.UnlikemostNSAIDs,benzydamineinhibitsprostaglandinsynthetase,notcyclooxygenase(COX).
| CasNo. | 132-69-4 |
|---|---|
| Purity | ≥98% |
| Formula | C19H23N3O•HCl |
| FormulaWt. | 345.87 |
| ChemicalName | N,N-Dimethyl-3-[[1-(phenylmethl)-1H-indazol-3-yl]oxy]-1-propanaminehydrochloride |
| IUPACName | 3-(1-benzylindazol-3-yl)oxy-N,N-dimethylpropan-1-amine;hydrochloride |
| Synonym | Benzindaminehydrochloride |
| MeltingPoint | 156-161°C |
| Solubility | Solubleinwater,ethanol,chloroform,n-butanolorDMSO |
| Appearance | WhitetoOff-WhiteCrystalPowder |
| StoreTemp | Ambient |
|---|---|
| ShipTemp | Ambient |
| MSDS | B1640MSDSPDF |
|---|---|
| InfoSheet | B1640InfoSheetPDF |
ChenCY,KuoCJ,LeeYW,etal.Benzydaminehydrochlorideonpostoperativesorethroat:ameta-analysisofrandomizedcontrolledtrials.CanJAnaesth.2014Mar;61(3):220-8.PMID:24263969.
KaravanaHizarcioğluSY,SezerB,GüneriP,etal.Efficacyoftopicalbenzydaminehydrochloridegelonoralmucosalulcers:aninvivoanimalstudy.IntJOralMaxillofacSurg.2011Sep;40(9):973-8.PMID:21549562.
FanakiNH,el-NakeebMA.Antimicrobialactivityofbenzydamine,anon-steroidanti-inflammatoryagent.JChemother.1992Dec;4(6):347-52.PMID:1287137.
